At the level of the Z lines between adjacent cardiac muscle cells, the intercalated disk composed of3 main junctional specializations complexes. 在Z线处,可见心肌细胞之间含有3种连接方式的特有连接结构&润盘。
Cx43 positive granules distributed irregularly in cell side surface and cytoplasm as well as intercalated disk in adult atrium. 2成人Cx43表达在心房肌非均质分布于细胞侧面连接处和端闰盘处;
In ventricular bands Purkinje cells could be seen in groups under TEM, among Purkinje cells typical intercalated disk structure was formed in some parts. 电镜下可见Purkinje细胞群,细胞之间存在着特化连接,有些部位形成典型的闰盘结构。
Results Compared with adult group, aging group: ( 1) The nuclei were indented, myofibril were arranged irregularly, intercalated disk were separated, mitochondria and sarcoplasmic reticulum were swelled, lipofuscin and residual body were increased. 结果与成年组比较,老龄组大鼠心肌改变:(1)核有切痕、肌原纤维不规整、闰盘离解、线粒体和肌浆网肿胀、脂褐素和残余体增多。
Conclusion The present paper demonstrated that the N-cadherin expression exists progressively with ages and the changing pattern of N-cadherin is closely related with development of the intercalated disk in rat myocardium. 结论在大鼠心肌发育过程中,Ncadherin的表达存在增龄变化;以Ncadherin介导的细胞黏合连接与闰盘的发育有着密切的联系;
Conclusion: The Cx43 rearrangements were confined to the intercalated disk following the heart development of mice, with gradually decreased density. 结论:小鼠心肌细胞Cx43分布随心脏发育逐渐向闰盘处重排,其密度逐渐下降。
Conclusion The expression of Cx43 is transferred from cytoplasm and surface of the cardiocyte to intercalated disk. 结论随着年龄的增长Cx43从细胞侧表面向端-端闰盘处转移。
Treated with Shenmai injection, it could alleviate cardiomyocyte degeneration in infarcted region; myofibril and intercalated disk were more regularly than the model group. Mitochondria swelled, crista lightly ruptured even vacuolization, but it was more alleviated than model group in corresponding time. 参麦注射液治疗后,梗死区心肌细胞变性程度减轻,肌原纤维排列较模型组规则,闰盘较整齐,线粒体虽仍有肿胀、轻度峭断裂甚至空泡化,但较相应时间点模型组明显减轻。